Dichloromethylene diphosphonate
WebSep 1, 1996 · Dichloromethylene diphosphonate (MDPCl 2) encapsulated in multilamellar liposomes was selectively incorporated by macrophages, immediately transferred to … WebIt is shown ultrastructurally that intravenously injected and liposome-entrapped dichloromethylene diphosphonate (DMDP) causes marked damage to marginal zone macrophages in the mouse spleen which finally results in the elimination of these cells.
Dichloromethylene diphosphonate
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WebRats received a single intravenous injection with liposome-encapsulated dichloromethylene diphosphonate (C12MDP). This treatment resulted in the … WebDMDP is ingested by phagocytic cells when entrapped in liposomes. Once phagocytized the liposomal membranes are digested and the drug is released into the cell and is ready for action. In vitro, even low doses of liposome-entrapped DMDP caused an significant reduction in cell numbers.
WebAbstract Dichloromethylene diphosphonate (Cl2MDP), an inhibitor of osteoclast activity, was evaluated for its ability to decrease the excessive mobilization of skeletal calcium … WebIt is shown ultrastructurally that intravenously injected and liposome-entrapped dichloromethylene diphosphonate (DMDP) causes marked damage to marginal zone …
WebDichloromethylene diphosphonate can be used for temporary elimination of macrophages in the spleen when administered after entrapment in liposomes. No comparable effect on the macrophages of the spleen was observed with free dichloromethylene diphosphonate or in the case of empty liposomes. Web匡德宣， 王文广， 孙晓梅， 代解杰(中国医学科学院/北京协和医学院医学生物学研究所树鼩种质资源中心，云南省重大传染 ...
WebLiposomes containing the drug dichloromethylene diphosphonate (Cl2MDP) can eliminate phagocytic cells, such as macrophages, when injected in vivo. In this paper we report that Cl2MDP-containing liposomes have been used experimentally to determine the extent to which cutaneous macrophages participate …
WebJan 15, 2003 · Liposomally encapsulated clodronate (dichloromethylene diphosphonate) has previously been found to be a potent antimacrophage agent. It … diamond resorts discount codesWebDisodium (dichloromethylene)di phosphonate. Molecular Formula CCl 2 Na 2 O 6 P 2; Average mass 286.841 Da; Monoisotopic mass 285.835358 Da; ChemSpider ID 19958758 diamond resorts deedback policyWebDichloromethylene diphosphonate (Cl 2 MDP) is a synthetic compound related in structure to inorganic pyrophosphate but is resistant to enzymatic and chemical … diamond resorts dream vacation certificateWebPhosphonic acid, (dichloromethylene)bis-, disodium salt CH2Cl2Na2O6P2 CID 73554303 - structure, chemical names, physical and chemical properties, classification, patents, literature, biological activities, … cisco catalyst uptimeWebKnow about technical details of Diphosphonate, Dichloromethylene like: chemical name, chemistry structure, formulation, uses, toxicity, action, side effects and more at Pharmacompass.com. Technical details about Diphosphonate, Dichloromethylene, learn more about the structure, uses, toxicity, action, side effects and more cisco catalyst switch default loginWebDichloromethylene diphosphonate (clodronate), a new compound, has powerful activity against osteoclasts and has been used successfully to treat hypercalcemia associated with cancer. We studied... diamond resorts drug test typeWebIt is shown ultrastructurally that intravenously injected and liposome-entrapped dichloromethylene diphosphonate (DMDP) causes marked damage to marginal zone macrophages in the mouse spleen which finally results in the elimination of these cells. Marginal zone lympohocytes are also affected by this treatment, probably as a result of … cisco catalyst reboot